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A Novel Imaging-guided High-Intensity Focused Ultrasound System for Treatment of Breast Tumors

  • Date: 2021-09-13
  • Update: 2021-09-13
  • Source: 國家衛生研究院
  • Views: 41

A Novel Imaging-guided High-Intensity Focused Ultrasound System for Treatment of Breast Tumors

 

September 13, 2021

 

Breast cancer is the world’s most common cancer among women. Clinical treatment modalities include surgery, radiotherapy, chemotherapy, hormone therapy, targeted therapy and combination therapy. However, women with breast cancer suffer from a risk of complications, a high re-excision rate, an occasional need for breast reconstruction after surgery, and possible side effects from radiation and chemotherapy.

 

A team led by Dr. Gin-Shin Chen of the National Health Research Institutes of Taiwan has developed a prototype ring high-intensity focused ultrasound (HIFU) system for noninvasive breast ablation. Besides the system requiring no anesthesia use or hospitalization, having low side effects, and leaving no skin scars, the innovative design of the ring HIFU transducer has four advantages: (1) a low risk of HIFU damage to chest tissue, lung, or heart due to the lateral acoustic paths of the ring transducer; (2) reduced treatment time because of volumetric ablation by switching different focusing patterns of the ring transducer; (3) skin burn of the breast is prevented by the large acoustic window of the ring transducer; and (4) high-precision ablation under imaging guidance. The ring HIFU system has been integrated with the MRI system, already performing MR-guided HFU ablation in rabbit legs in vivo; the experimental results verified the feasibility of the ring HIFU system.

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